Research - #3964587

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The Faculty of Medicine OWL has the following job opening:

Research Position for the international project „TumorOUT“

ID: Wiss23311

• starting: as soon as possible
• fulltime
• salary according to Remuneration level 13 TV-L
• fixed-term

In the joint project TumorOUT, an innovative mRNA vaccine against lung cancer is being developed. Together with research partners from Spain, France, Israel and Germany, immunotherapeutic tools based on targeted nanoparticles are being designed. These will be loaded with mRNA + siRNA constructs specifically designed for metabolic modulation of antigen-presenting cells (APC) in non-small cell lung carcinomas. By reconstructing conditions in the tumor microenvironment, effective personalized therapy will be realized. At the Bielefeld site, spatial distributions of metabolites within the tumor microenvironment (TMU) will be investigated using imaging techniques (MALDI-MSI, histology, microscopy, and others). The goal of the project is to elucidate the effects of nanoimmunotherapy on metabolic interactions within the tumor microenvironment and to document the success of the therapy.

Your Tasks

• research on imaging of metabolic processes in tumor tissues and cell cultures (70 %)
• communication and organization of a workshop in Bielefeld, and practical exchange with partners in the international EU project (10 %)
• publication and presentation of research results (20 %)

Employment is conducive to scientific qualification.

We offer

• salary according to Remuneration level 13 TV-L
• fixed-term Until 31.03.2026 with the possibility of extension up to 3 years contract duration in case of project extension (§ 2 (1) sentence 2 of the WissZeitVG; in accordance with the provisions of the WissZeitVG and the Agreement on Satisfactory Conditions of Employment, the length of contract may differ in individual cases)
• fulltime

• internal and external training opportunities
• variety of health, consulting and prevention services
• reconcilability of family and work
• job security
• constant place of work (Bielefeld) without frequent travel activities
• flexible working hours
• job ticket for regional public transport network, good transport connection
• supplementary company pension
• collegial working environment
• open and pleasant working atmosphere
• exciting, varied tasks
• various offers (canteen, cafeteria, restaurants, Uni-Shop, ATM, etc.)

Your Profile We expect

• completed scientific university studies (Master's degree or comparable) in a scientific field of study (Biology, Biochemistry, Molecular Medicine or comparable)
• research experience and completed PhD in one of the above mentioned subjects
• theoretical knowledge in tumor biology as well as immunology
• creativity and fun in developing and optimizing methods for imaging mass spectrometry (e.g. timsTOF flex MALDI2 and other equipment of CF Omics of Bielefeld University)
• very good skills of written and spoken English
• willingness and ability to work in an international research team
• ability to work in a team and independently
• gender and diversity competence

Preferred experience and skills

• practical experience in one or more of the following areas of work:
  • handling of human and animal tissues (fresh frozen and FFPE)
  • histology
  • imaging mass spectrometry
  • immunohistochemical methods in microscopy
• experience in bioinformatics and analysis of large data sets (Data Science) and/or image data (e.g. CellProfiler or QuPath etc.)
• theoretical knowledge in tumor biology, as well as immunology

Application Procedure

We are looking forward to receiving your application. To apply, please use our online form via the application button below. Otherwise, you can send your complete application with the identification code Wiss23311 to the postal address listed on the right site.

application deadline: 06.07.2023

Contact
Dr. Hanna Bednarz
+49 521 106 67498
[email protected]

Postal Address
Universität Bielefeld
Markus Zöller
Postfach 10 01 31
33501 Bielefeld Bielefeld University has received a number of awards for its achievements as an equal-opportunity employer and has been recognized as a family-friendly university. The university welcomes applications from women. This is particularly true with regard both to academic and technical posts as well as positions in information technology as well as the skilled crafts and trades. Applications are handled according to the provisions of the state statutes on equal opportunity. Applications from suitably qualified handicapped and severely handicapped persons are explicitly encouraged.

At Bielefeld University on request positions can be carried out with reduced working hours as long as this does not conflict with official needs

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